HPSE, heparanase, 10855

N. diseases: 393; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.050 Biomarker group BEFREE Roles for heparanase in stroke, Alzheimer's disease, and glioma growth have been described; roles for heparanase in other disease such as multiple sclerosis (MS) are less well established. 28778449 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.050 GeneticVariation group BEFREE Polymorphisms in HPA-I and MTHFR may have important predisposing roles in the development of pediatric stroke. 18836720 2009
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.050 GeneticVariation group BEFREE This is the first evidence demonstrating differential association of the common 4 HPA gene variants and specific HPA genotype combinations with stroke. 18383324 2008
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.050 GeneticVariation group BEFREE This is the first evidence demonstrating differential association of the common 5 HPA gene variants with stroke, with HPA-1b and HPA-5b representing strong genetic risk factors. 18057877 2008
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.050 Biomarker group BEFREE Our results indicate that the HPA-1, HPA-2, HPA-3, and HPA-5 polymorphisms are not associated with an increased risk for stroke. 9227689 1997