HPSE, heparanase, 10855

N. diseases: 393; N. variants: 12
Disease: Thrombocytopenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040034
Disease: Thrombocytopenia
Thrombocytopenia 		0.050 Biomarker phenotype BEFREE HPA1-a) cause life-threatening anemia or thrombocytopenia in the developing fetus or newborn. 26961360 2016
CUI: C0040034
Disease: Thrombocytopenia
Thrombocytopenia 		0.050 Biomarker phenotype BEFREE In this study our aims were to find whether other allele variants of the β subunit of the HLA-DR family specifically focused on the HLA residues that bind Position 33 of the HPA-1 integrin contribute to FNAIT development and affect response to treatment and whether coexistence of both anti-HPA-1a and anti-HLA class I specific against the father's antigens leads to a more severe thrombocytopenia in the newborn. 22671039 2013
CUI: C0040034
Disease: Thrombocytopenia
Thrombocytopenia 		0.050 Biomarker phenotype BEFREE Genotyping for HPA 1-5 systems was performed in pairs of mother/neonates with and without thrombocytopenia. 17207231 2007
CUI: C0040034
Disease: Thrombocytopenia
Thrombocytopenia 		0.050 Biomarker phenotype BEFREE HPA-1 carrier status and thrombocytopenia in preterm infants with a birth weight below 1500 grams. 12012640 2002
CUI: C0040034
Disease: Thrombocytopenia
Thrombocytopenia 		0.050 Biomarker phenotype BEFREE Differences in the children's HPA type (HPA-1, -2, -3, -5) did not correlate with thrombocytopenia. 10760207 2000