HPSE, heparanase, 10855

N. diseases: 393; N. variants: 12
Disease: Esophageal carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		0.050 AlteredExpression disease BEFREE Expression of heparanase mRNA in anti-sense oligonucleotide-transfected human esophageal cancer EC9706 cells. 16097072 2005
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		0.050 Biomarker disease BEFREE Up-regulation of COX-2 mRNA and protein was observed in esophageal cancer cells transfected with heparanase cDNA. 16299228 2005
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		0.050 Biomarker disease BEFREE Our results suggest that cytoplasmic heparanase appears to be a useful prognostic marker in patients with esophageal cancer and that nuclear heparanase protein may play a role in differentiation. 15286661 2004
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		0.050 AlteredExpression disease BEFREE All 30 esophageal cancer cell lines expressed heparanase mRNA. 11295076 2001
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		0.050 AlteredExpression disease BEFREE Increased heparanase expression in T.Tn human esophageal cancer cells and A549 human lung cancer cells after infection with an adenovirus vector expressing the human heparanase gene (Ad-S/hep) was specifically inhibited by simultaneous infection with Ad-AS/hep in a dose-dependent manner. 11691803 2001