HPSE, heparanase, 10855

N. diseases: 393; N. variants: 12
Disease: Pancreatic carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 AlteredExpression disease BEFREE Heparanase expression in blood is sensitive to monitor response to anticancer treatment in pancreatic cancer, a pilot study. 29153700 2018
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 Biomarker disease BEFREE Taken together, our results demonstrated that gemcitabine-induced HPA1 promotes proliferation and invasion of PC cells through activating EGFR, implying that HPA1 may serve as promising therapeutic target in the treatment of PC. 28938567 2017
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 Biomarker disease BEFREE We assume that HPSE plays a crucial role for the aggressiveness of pancreatic cancer. 18704599 2008
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 AlteredExpression disease BEFREE Increased serum HPR1 activity was associated with a shorter survival in patients with pancreatic carcinoma patients. 16388520 2006
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 AlteredExpression disease BEFREE In the present study, we examined HPR1 expression in pancreatic cancer by using in situ hybridization and tested whether HPR1 expression correlated with any clinicopathlogic parameters. 11992801 2002
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 Biomarker disease BEFREE Our results suggest, that heparanase promotes cancer cell invasion in pancreatic carcinoma and could be used as a prognostic indicator for postoperative survival of patients. 11953884 2002