HPSE, heparanase, 10855

N. diseases: 393; N. variants: 12
Disease: Childhood Medulloblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma 		0.030 Biomarker disease BEFREE However, HPSE roles in MB invasive pathways have not been investigated. 17550129 2007
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma 		0.030 Biomarker disease BEFREE These studies support the role of p75(NTR) and HPSE-1 as two novel molecular determinants involved in the biology and clinical progression of MB. 16826429 2006
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma 		0.030 Biomarker disease BEFREE Taken together, our data extend the body of evidence that invasion and expression/functionality of heparanase, in a context linked to TrkC and p75NTR, may play critical roles in the disease progression of medulloblastoma. 16077909 2005