Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0234985
Disease: Mental deterioration
Mental deterioration
0.030 GeneticVariation phenotype BEFREE The combined effects of metabolic syndrome and the apolipoprotein E and CYP46 genotypes on the risk of cognitive decline has yet to be determined among Taiwanese Chinese. 24924840 2014
CUI: C0234985
Disease: Mental deterioration
Mental deterioration
0.030 GeneticVariation phenotype BEFREE The integrated effect of the cholesterol and CYP46 genotypes on the risk of cognitive decline needs to be determined. 21729100 2011
CUI: C0234985
Disease: Mental deterioration
Mental deterioration
0.030 GeneticVariation phenotype BEFREE These findings provide direct evidence that CYP46 and ApoE polymorphisms synergically increase the risk for AD development, and influence on the rate of cognitive decline. 15165699 2004