|
Psoriasis
|
0.130 |
GeneticVariation
|
disease |
BEFREE |
Hypermethylated genes found included GTPase-related genes, while hypomethylated genes included HCP5, which encodes a lncRNA within the MHC region, previously associated with genetic risk for psoriasis and toxic epidermal necrolysis.
|
31128893 |
2019 |
|
Psoriasis
|
0.130 |
Biomarker
|
disease |
BEFREE |
Thus, the data suggested that HCP5, TNIP1 and TNFAIP3 may play a role in common pathogenic of psoriasis in Chinese and confer risk factors for psoriasis in various ethnic populations.
|
25264125 |
2014 |
|
Psoriasis
|
0.130 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
|
18369459 |
2008 |
|
Psoriasis
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
|
18369459 |
2008 |
|
Psoriasis
|
0.130 |
GeneticVariation
|
disease |
BEFREE |
However, rs2395029 encoding the G2V polymorphism within the class I gene HCP5 (combined P = 2.13x10(-26) in U.S. cases) yielded the highest ORs with both PS and PSA (4.1 and 3.2 respectively).
|
18369459 |
2008 |
|
Graves Disease
|
0.120 |
GeneticVariation
|
disease |
BEFREE |
Regression analysis showed that patients with higher number of HCP5 risk alleles tend to have a significantly earlier onset of GD (P = 6.9 × 10<sup>-5</sup> ).
|
30358895 |
2019 |
|
Graves Disease
|
0.120 |
GeneticVariation
|
disease |
GWASCAT |
Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study.
|
26151496 |
2015 |
|
Graves Disease
|
0.120 |
Biomarker
|
disease |
BEFREE |
HCP5 and MAGI3 SNPs were further correlated with age of GD onset.
|
25345847 |
2015 |
|
Lupus Erythematosus, Systemic
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
We describe a novel significant association between HCP5 locus and SLE susceptibility [rs3099844: P = 0.01, OR = 2.06 (95% CI: 1.18-3.6)].
|
25369137 |
2014 |
|
Lupus Erythematosus, Systemic
|
0.110 |
GeneticVariation
|
disease |
GWASDB |
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
|
24871463 |
2014 |
|
Carpal Tunnel Syndrome
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome.
|
30833571 |
2019 |
|
Herpes zoster disease
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype.
|
30298529 |
2019 |
|
Chemical and Drug Induced Liver Injury
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles.
|
30661239 |
2019 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.
|
28552196 |
2017 |
|
Child Development Disorders, Pervasive
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Squamous cell carcinoma of lung
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
Physical Activity Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
28448500 |
2017 |
|
Platelet Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Polymyositis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.
|
26362759 |
2016 |
|
Lymphocyte Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Eosinophil count procedure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Blood basophil count (lab test)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Myositis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.
|
26291516 |
2015 |