C1QL1, complement C1q like 1, 10882

N. diseases: 73; N. variants: 1
Disease: Depressive disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.050 Biomarker disease BEFREE Corticotropin-releasing factor binds with high affinity to CRF receptor 1 (CRFR1) and is implicated in stress-related mood disorders such as anxiety and depression. 30499109 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.050 Biomarker disease BEFREE CRF is a stress-related neuropeptide whose dysregulation has been associated with depression. 31312123 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.050 Biomarker disease BEFREE The corticotropin-releasing factor (CRF, or corticotropin-releasing hormone) and arginine vasopressin systems have been implicated in the pathophysiology of anxiety and depressive disorders and response to antidepressant treatment. 20368512 2010
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.050 Biomarker disease BEFREE More refined analysis of the HPA system revealed that corticosteroid receptor (CR) signaling is impaired in major depression, resulting among other changes, in increased production and secretion of corticotropin-releasing hormone (CRH, also frequently abbreviated CRF) in various brain regions postulated to be involved in the causality of depression. 11027914 2000
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.050 Biomarker disease BEFREE CRF overproduction has been implicated in affective disorders, such as depression and anorexia nervosa, and may lead to Cushing's syndrome. 1597149 1992