PROKR1, prokineticin receptor 1, 10887

N. diseases: 27; N. variants: 3
Disease: early pregnancy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0747845
Disease: early pregnancy
early pregnancy 		0.020 Biomarker phenotype BEFREE During the last decade, studies indicated that the expression patterns of the prokineticin receptor (PKR1 and PKR2) are closely related to early pregnancy. 26984842 2016
CUI: C0747845
Disease: early pregnancy
early pregnancy 		0.020 GeneticVariation phenotype BEFREE In conclusion, PROKR1 (I379V) and PROKR2 (V331M) variants conferred lower risk for RM and may play protective roles in early pregnancy by altering calcium signaling and facilitating cell invasiveness. 23687280 2013