PPARGC1A, PPARG coactivator 1 alpha, 10891

N. diseases: 350; N. variants: 42
Disease: Coronary heart disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 AlteredExpression disease BEFREE Upregulation of PGC-1α by ZLN005 has been shown to have beneficial effect in a diabetic mouse model and in a coronary artery disease model in vitro. 29334584 2018
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 AlteredExpression disease BEFREE PGC-1α (Peroxisome Proliferator-Activated Receptor γ Coactivator 1-α) Overexpression in Coronary Artery Disease Recruits NO and Hydrogen Peroxide During Flow-Mediated Dilation and Protects Against Increased Intraluminal Pressure. 28533333 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 GeneticVariation disease BEFREE Association of combined genetic variations in PPARγ, PGC-1α, and LXRα with coronary artery disease and severity in Thai population. 27016616 2016
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 GeneticVariation disease BEFREE Association between PPARGC1A gene polymorphisms and coronary artery disease in a Chinese population. 18565194 2008