PPARGC1A, PPARG coactivator 1 alpha, 10891

N. diseases: 350; N. variants: 42
Disease: Osteopenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029453
Disease: Osteopenia
Osteopenia 		0.020 Biomarker disease BEFREE Conversely, induction of PGC-1α attenuated osteoporotic bone loss and MAT accumulation. 30017591 2018
CUI: C0029453
Disease: Osteopenia
Osteopenia 		0.020 Biomarker disease BEFREE (2018) show that PGC-1α regulates marrow mesenchymal stromal cell lineage allocation in vivo, inhibiting marrow adipogenesis and associated bone loss in the aging skeleton and following ovariectomy-induced osteoporosis. 30075123 2018