FERMT2, fermitin family member 2, 10979

N. diseases: 80; N. variants: 10
Disease: Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE However, currently, no animal model to study the role of Kindlin-2 in the carcinogenesis of mammary gland is available. 30460471 2019
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE Knockdown of Kindlin‑2 also inhibits ACHN cell proliferation in vitro and tumorigenesis in vivo. 28677779 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE In conclusion, these results demonstrate that these three focal adhesion components, particularly kindlin‑2, may contribute to the carcinogenesis of esophageal squamous cells. 27748861 2016
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE Kindlin-2 promotes carcinogenesis through regulation of cell-cell and cell-extracellular matrix adhesion. 27713156 2016
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE Kindlin-2, a regulator of integrins, recently has been found to be involved in the tumorigenesis. 25633062 2015
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE The number of DMRs in the vicinity of gene transcription start sites correlated with the level of expression of TACC1, CLDN1, and PLEKHC1 (FERMT2) genes, which have been linked to carcinogenesis. 21821115 2011