DEPP1, DEPP1 autophagy regulator, 11067

N. diseases: 23; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.310 AlteredExpression disease BEFREE Our data provided the first evidence that C10orf10 expression was frequently decreased in breast cancer tissues, and low expression of C10orf10 may be an important prognostic factor for poorer survival time of breast cancer patients. 24936657 2014
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.310 AlteredExpression disease BEFREE Our data provided the first evidence that C10orf10 expression was frequently decreased in breast cancer tissues, and low expression of C10orf10 may be an important prognostic factor for poorer survival time of breast cancer patients. 24936657 2014
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.310 Biomarker disease CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.310 Biomarker disease CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.300 Biomarker disease CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642 2011
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker disease CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642 2011
CUI: C0023794
Disease: Lipoidosis
Lipoidosis
0.300 Biomarker disease CTD_human Determination of phospholipidosis potential based on gene expression analysis in HepG2 cells. 17175557 2007
CUI: C0023794
Disease: Lipoidosis
Lipoidosis
0.300 Biomarker disease CTD_human Improved toxicogenomic screening for drug-induced phospholipidosis using a multiplexed quantitative gene expression ArrayPlate assay. 16919414 2006
CUI: C0023794
Disease: Lipoidosis
Lipoidosis
0.300 Biomarker disease CTD_human A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system. 15342952 2005
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker disease CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.300 Biomarker group CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human
0.300 Biomarker disease CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 AlteredExpression group BEFREE Importantly, in a xenograft mouse model of human colon cancer, we further confirmed that baicalin treatment dramatically inhibited tumor growth, which was due to the induction of tumor cellular senescence via the upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling in vivo. 29440765 2018
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.020 Biomarker disease BEFREE Targeting FOXO3/DEPP-triggered autophagy is a promising strategy to sensitize neuroblastoma cells to chemotherapy. 28545464 2017
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.020 Biomarker disease BEFREE Targeting FOXO3/DEPP-triggered autophagy is a promising strategy to sensitize neuroblastoma cells to chemotherapy. 28545464 2017
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma
0.020 Biomarker disease BEFREE Targeting FOXO3/DEPP-triggered autophagy is a promising strategy to sensitize neuroblastoma cells to chemotherapy. 28545464 2017
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.020 Biomarker disease BEFREE We report for the first time that DEPP regulates ROS detoxification and localizes to peroxisomes and mitochondria in neuroblastoma cells. 25261981 2014
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.020 Biomarker disease BEFREE We report for the first time that DEPP regulates ROS detoxification and localizes to peroxisomes and mitochondria in neuroblastoma cells. 25261981 2014
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma
0.020 Biomarker disease BEFREE We report for the first time that DEPP regulates ROS detoxification and localizes to peroxisomes and mitochondria in neuroblastoma cells. 25261981 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 GeneticVariation group BEFREE Possible functions of the highly expressed gene Depp include tumor vascularization. 17486380 2007
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation disease BEFREE Recently, small studies of colorectal carcinomas (CRCs) have suggested an incidence of EML4-ALK translocations of 0.4% to 2.4% and FIG-ROS1 translocations of 0.8%. 24992173 2015
CUI: C0235782
Disease: Gallbladder Carcinoma
Gallbladder Carcinoma
0.010 GeneticVariation disease BEFREE We found that six out of 65 (9%) BTC patients were positive for the FIG-ROS1 fusion, comprising two out of 14 (14%) gallbladder carcinoma (GBC) patients and four out of 25 (16%) extrahepatic cholangiocarcinoma (ECC) patients. 25231053 2014
CUI: C0740277
Disease: Bile duct carcinoma
Bile duct carcinoma
0.010 Biomarker disease BEFREE We developed a new, quick, specific, and sensitive PCR test to screen for the FIG-ROS1 fusion and applied it to a series of Italian patients with bile duct carcinoma (BTC). 25231053 2014
CUI: C3805278
Disease: Extrahepatic Cholangiocarcinoma
Extrahepatic Cholangiocarcinoma
0.010 Biomarker disease BEFREE In conclusion, 14-16% of GBC and ECC were positive for FIG-ROS1. 25231053 2014
CUI: C0020615
Disease: Hypoglycemia
Hypoglycemia
0.010 Biomarker disease BEFREE Indeed, the α-cell-specific insulin receptor knockout (αIRKO) mouse manifests hypersecretion of glucagon in the postprandial stage and exhibits defective secretion in fasting-induced hypoglycaemia, together mimicking the α-cell defects observed in type 2 diabetes. 21824253 2011