KAT7, lysine acetyltransferase 7, 11143

N. diseases: 35; N. variants: 2
Disease: Cachexia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006625
Disease: Cachexia
Cachexia 		0.010 Biomarker phenotype BEFREE Overexpression of NUP98-HBO1 in murine HSC/progenitors (HSC/Ps) induced diverse CMML phenotypes, such as severe leukocytosis, increased CD115<sup>+</sup> Ly6C<sup>high</sup> monocytes (an equivalent subpopulation to human classical CD14<sup>+</sup> CD16<sup>-</sup> monocytes), macrocytic anemia, thrombocytopenia, megakaryocyte-lineage dysplasia, splenomegaly, and cachexia. 30944097 2019