CHI3L1, chitinase 3 like 1, 1116

N. diseases: 420; N. variants: 9
Disease: Coronary heart disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 AlteredExpression disease BEFREE High serum YKL-40 level positively correlates with coronary artery disease. 28097894 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 Biomarker disease BEFREE These results provide a novel regulatory mechanism of circulating miR-24 in regulating YKL-40 levels in DM2-CHD, may serve as a biomarker for predicting patients with DM2 and CHD. 28968969 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 AlteredExpression disease BEFREE Patients with CHD had higher YKL-40 levels compared to controls and those with acute myocardial infarction had the highest levels of YKL-40 compared to patients with either stable or unstable angina pectoris (all p<0.01). 22433444 2012
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.040 AlteredExpression disease BEFREE Genetic polymorphisms in chitinase 3-like 1 (CHI3L1) are associated with circulating YKL-40 levels, but not with angiographic coronary artery disease in a Chinese population. 21257319 2011