CHI3L1, chitinase 3 like 1, 1116

N. diseases: 420; N. variants: 9
Disease: Liver diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023895
Disease: Liver diseases
Liver diseases 		0.050 AlteredExpression group BEFREE Serum levels of CHI3L1 are strongly correlated with hepatic fibrosis progression during many liver diseases. 31250532 2019
CUI: C0023895
Disease: Liver diseases
Liver diseases 		0.050 AlteredExpression group BEFREE Serum YKL-40 levels are increased in liver diseases and our aim was to investigate YKL-40 levels in pregnant women with ICP. 30688121 2019
CUI: C0023895
Disease: Liver diseases
Liver diseases 		0.050 GeneticVariation group BEFREE YKL-40-gene polymorphism affects acute cellular rejection and fibrosis progression after transplantation for hepatitis C virus-induced liver disease. 22989351 2013
CUI: C0023895
Disease: Liver diseases
Liver diseases 		0.050 GeneticVariation group BEFREE By sequence analysis of the promoter for YKL40, an inflammatory marker upregulated in patients with chronic liver diseases with fibrosis, adjacent binding sites for nuclear factor of Kappa B/P65 and CCAAT/enhancer-binding protein alpha (CEBPα) were identified. 23226395 2012
CUI: C0023895
Disease: Liver diseases
Liver diseases 		0.050 GeneticVariation group BEFREE The absence of an association between YKL-40 promoter polymorphisms and baseline liver disease severity as well as with the risk of liver disease progression over time suggests that this polymorphism is not associated with disease progression in CHC patients with established fibrosis. 22103814 2012