PSIP1, PC4 and SFRS1 interacting protein 1, 11168

N. diseases: 210; N. variants: 2
Disease: Impaired cognition ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.060 Biomarker disease BEFREE Removal of p75 Neurotrophin Receptor Expression from Cholinergic Basal Forebrain Neurons Reduces Amyloid-β Plaque Deposition and Cognitive Impairment in Aged APP/PS1 Mice. 30374941 2019
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.060 GeneticVariation disease BEFREE Reversal of Cognitive Impairment in gp120 Transgenic Mice by the Removal of the p75 Neurotrophin Receptor. 31543761 2019
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.060 Biomarker disease BEFREE The p75 neurotrophin receptor might mediate sepsis-induced synaptic and cognitive impairments. 29604364 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.060 Biomarker disease BEFREE The p75 neurotrophin receptor regulates cranial irradiation-induced hippocampus-dependent cognitive dysfunction. 28380447 2017
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.060 Biomarker disease BEFREE Inhibition of p75 neurotrophin receptor does not rescue cognitive impairment in adulthood after isoflurane exposure in neonatal mice. 28969308 2017
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.060 Biomarker disease BEFREE Degeneration of basal forebrain cholinergic neurons contributes significantly to the cognitive deficits associated with Alzheimer's disease (AD) and has been attributed to aberrant signaling through the neurotrophin receptor p75 (p75NTR). 25153701 2014