NISCH, nischarin, 11188

N. diseases: 49; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.320 Biomarker group CTD_human Expression of long noncoding RNA MALAT1 correlates with increased levels of Nischarin and inhibits oncogenic cell functions in breast cancer. 29912916 2018
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.320 Biomarker group BEFREE Our studies, for the first time, demonstrate functional interaction between LKB1 and Nischarin to inhibit cell migration and breast tumor progression. 23572524 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.320 AlteredExpression group BEFREE Normal human breast tissue samples had statistically significantly higher expression of nischarin mRNA compared with tumor tissue samples (mean level in normal breast = 50.7 [arbitrary units], in breast tumor = 16.49 [arbitrary units], difference = 34.21, 95% confidence interval [CI] = 11.63 to 56.79, P = .003), and loss of heterozygosity was associated with loss of nischarin expression. 21917605 2011