RNF139, ring finger protein 139, 11236

N. diseases: 36; N. variants: 1
Disease: Renal carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma 		0.040 GeneticVariation disease BEFREE The TRC8 gene, which was previously shown to be disrupted by a 3;8 chromosomal translocation in hereditary kidney cancer, encodes for an endoplasmic reticulum-resident E3 ligase. 22689053 2013
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma 		0.040 Biomarker disease BEFREE RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene. 17016439 2007
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma 		0.040 Biomarker disease BEFREE Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5. 15735686 2005
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma 		0.040 Biomarker disease BEFREE Thus, VHL, TRC8, and JAB1 appear to be linked both physically and functionally and all three may participate in the development of kidney cancer. 12032852 2002