PTGDR2, prostaglandin D2 receptor 2, 11251

N. diseases: 60; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014457
Disease: Eosinophilia
Eosinophilia
0.020 Biomarker disease BEFREE The CRTH2 antagonist (OC000459) or dual CRTH2 and TP receptor antagonist (ramatroban) were effective in reducing eosinophilia, nasal mucosal swelling, and clinical symptoms of allergic rhinitis, with the latter drug registered for clinical use in this indication. 28612233 2017
CUI: C0014457
Disease: Eosinophilia
Eosinophilia
0.020 Biomarker disease BEFREE Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced eosinophilia in rats. 12975488 2003