PTGDR2, prostaglandin D2 receptor 2, 11251

N. diseases: 60; N. variants: 1
Disease: Allergic asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.040 Biomarker disease BEFREE Efficacy and safety of the CRTh2 antagonist AZD1981 as add-on therapy to inhaled corticosteroids and long-acting β<sub>2</sub>-agonists in patients with atopic asthma. 29765200 2018
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.040 Biomarker disease BEFREE Fevipiprant, an oral prostaglandin DP<sub>2</sub> receptor (CRTh2) antagonist, in allergic asthma uncontrolled on low-dose inhaled corticosteroids. 28838980 2017
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.040 Biomarker disease BEFREE AZD1981 is an orally bioavailable chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTh2) receptor antagonist progressed to phase II trials for the treatment of allergic asthma. 27558866 2017
CUI: C0155877
Disease: Allergic asthma
Allergic asthma 		0.040 GeneticVariation disease BEFREE Here, we assessed the association between CRTh2 rs533116 and allergic asthma, expression of CRTh2 and Th2 cytokine production. 22947041 2012