TREX1, three prime repair exonuclease 1, 11277

N. diseases: 241; N. variants: 36
Disease: AICARDI-GOUTIERES SYNDROME 5 (disorder) ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2749659
Disease: AICARDI-GOUTIERES SYNDROME 5 (disorder)
AICARDI-GOUTIERES SYNDROME 5 (disorder) 		0.200 Biomarker disease MGD The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA. 27496731 2016
CUI: C2749659
Disease: AICARDI-GOUTIERES SYNDROME 5 (disorder)
AICARDI-GOUTIERES SYNDROME 5 (disorder) 		0.200 Biomarker disease MGD Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response. 23972988 2013
CUI: C2749659
Disease: AICARDI-GOUTIERES SYNDROME 5 (disorder)
AICARDI-GOUTIERES SYNDROME 5 (disorder) 		0.200 Biomarker disease MGD Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis. 15254239 2004