Mental Depression
|
0.540 |
GeneticVariation
|
disease |
BEFREE |
Genetic variation in the cholinergic muscarinic-2 (M(2)) receptor gene (CHRM2) has been associated with the risk for developing depression.
|
20351719 |
2011 |
Mental Depression
|
0.540 |
Biomarker
|
disease |
PSYGENET |
Genetic variation in the cholinergic muscarinic-2 (M(2)) receptor gene (CHRM2) has been associated with the risk for developing depression.
|
20351719 |
2011 |
Mental Depression
|
0.540 |
Biomarker
|
disease |
RGD |
Expression profiling of a genetic animal model of depression reveals novel molecular pathways underlying depressive-like behaviours.
|
20830301 |
2010 |
Mental Depression
|
0.540 |
GeneticVariation
|
disease |
BEFREE |
Our data fail to support association with the CHRM2 polymorphisms previously implicated in the genetic aetiology of depression.
|
19181679 |
2009 |
Mental Depression
|
0.540 |
Biomarker
|
disease |
PSYGENET |
Our data fail to support association with the CHRM2 polymorphisms previously implicated in the genetic aetiology of depression.
|
19181679 |
2009 |
Mental Depression
|
0.540 |
GeneticVariation
|
disease |
BEFREE |
In this study, we evaluated whether genetic variation in the CHRM2 gene is also a risk factor for the correlated clinical characteristics of alcoholism and depression.
|
15229186 |
2004 |
Mental Depression
|
0.540 |
Biomarker
|
disease |
PSYGENET |
In this study, we evaluated whether genetic variation in the CHRM2 gene is also a risk factor for the correlated clinical characteristics of alcoholism and depression.
|
15229186 |
2004 |
Mental Depression
|
0.540 |
Biomarker
|
disease |
BEFREE |
These results are consistent with a gender-specific role of the CHRM2 gene in depression in women.
|
12116189 |
2002 |
Mental Depression
|
0.540 |
Biomarker
|
disease |
PSYGENET |
These results are consistent with a gender-specific role of the CHRM2 gene in depression in women.
|
12116189 |
2002 |
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
When compared to the general population, this genetic polymorphism was not found to be more common in alcohol dependence per se, which excludes the possibility of spurious association between CHRM2 and DT.
|
29478862 |
2018 |
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Studies continue to reveal other genes in which variants affect the risk of alcoholism or related traits, including GABRA2, CHRM2, KCNJ6 and AUTS2.
|
23712313 |
2013 |
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Discrete time survival analysis was used to assess the age-specific association of event-related oscillations (EROs) and CHRM2 gene variants on the onset of regular alcohol use and alcohol dependence.
|
23963516 |
2013 |
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The present study used group based trajectory modeling of auditory P300 data collected longitudinally from offspring in families with and without familial loading for AD to determine if specific trajectories would be associated with familial risk and CHRM2 variation.
|
23747232 |
2013 |
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Discrete time survival analysis was used to assess the age-specific association of event-related oscillations (EROs) and CHRM2 gene variants on the onset of regular alcohol use and alcohol dependence.
|
23963516 |
2013 |
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
The present study used group based trajectory modeling of auditory P300 data collected longitudinally from offspring in families with and without familial loading for AD to determine if specific trajectories would be associated with familial risk and CHRM2 variation.
|
23747232 |
2013 |
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
We report one such effort with respect to CHRM2, which codes for the cholinergic muscarinic 2 receptor and was of interest originally for its association with alcohol dependence.
|
21441226 |
2011 |
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Three single nucleotide polymorphisms (SNPs) of CHRM2 were genotyped using the TaqMan assay and analyzed with the severity of symptoms of alcohol dependence.
|
21176104 |
2011 |
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Three single nucleotide polymorphisms (SNPs) of CHRM2 were genotyped using the TaqMan assay and analyzed with the severity of symptoms of alcohol dependence.
|
21176104 |
2011 |
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
We report one such effort with respect to CHRM2, which codes for the cholinergic muscarinic 2 receptor and was of interest originally for its association with alcohol dependence.
|
21441226 |
2011 |
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
LHGDN |
Association analyses of a candidate gene, CHRM2, previously of interest in the Collaborative Study on the Genetics of Alcoholism, suggest that it is involved in a general externalizing phenotype.
|
18316677 |
2008 |
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
The evidence for association between CHRM2 and alcohol dependence came entirely from the subgroup of individuals with comorbid drug dependence.
|
17567401 |
2007 |
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
(d) Examination of family-based samples has identified several genes including GABRA2 and CHRM2 thought to be associated with alcohol dependence.
|
16612210 |
2006 |
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Six markers at CHRM2 and 38 ancestry-informative markers (AIMs) were genotyped in a sample of 871 subjects, including 333 healthy controls [287 European-Americans (EAs) and 46 African-Americans (AAs)] and 538 AD and/or DD subjects (415 with AD and 346 with DD and 382 EAs and 156 AAs).
|
16000316 |
2005 |
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In this study, we evaluated whether genetic variation in the CHRM2 gene is also a risk factor for the correlated clinical characteristics of alcoholism and depression.
|
15229186 |
2004 |
Depressive disorder
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
Genetic variation in the cholinergic muscarinic-2 (M(2)) receptor gene (CHRM2) has been associated with the risk for developing depression.
|
20351719 |
2011 |