CHRM2, cholinergic receptor muscarinic 2, 1129

N. diseases: 91; N. variants: 10
Disease: Substance Dependence ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038580
Disease: Substance Dependence
Substance Dependence 		0.320 GeneticVariation disease BEFREE This group also showed a greater prevalence of a CHRM2 genotype previously associated with substance dependence and Major Depressive Disorder as well as a modest elevation on a non-planning impulsiveness scale. 24530440 2014
CUI: C0038580
Disease: Substance Dependence
Substance Dependence 		0.320 Biomarker disease CTD_human Altered neural cholinergic receptor systems in cocaine-addicted subjects. 20393457 2010
CUI: C0038580
Disease: Substance Dependence
Substance Dependence 		0.320 Biomarker disease BEFREE We assessed dimensions of the five-factor model of personality, and genotyped six CHRM2 markers and 38 unlinked ancestry-informative markers in 239 subjects with SD [173 European-Americans (EAs) and 66 African-Americans (AAs)] and 275 healthy subjects (237 EAs and 38 AAs). 17468496 2007