AZIN2, antizyme inhibitor 2, 113451

N. diseases: 187; N. variants: 2
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE Overall, these results highlight EV20/MMAF as a novel ADC with promising therapeutic efficacy, warranting extensive pre-clinical evaluation in melanoma with high levels of HER-3 expression. 29550398 2018
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE We assessed the therapeutic combination of an antibody-drug conjugate (ADC) targeting the endothelin B receptor (EDNRB) with small-molecule inhibitors of the MAP kinase signaling pathway in melanoma. 24651527 2014
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE An ADC targeting the EDNBR is highly efficacious in preclinical models of melanoma. 21245091 2011