DisGeNET - a database of gene-disease associations

CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, 1138

N. diseases: 110; N. variants: 40

Disease: Anxiety Disorders ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0003469
Disease:	Anxiety Disorders

Anxiety Disorders

0.300

Biomarker

group

CTD_human

Knockout of alpha 5 nicotinic acetylcholine receptors subunit alters ethanol-mediated behavioral effects and reward in mice.

29944862

2018

CUI:	C0003469
Disease:	Anxiety Disorders

Anxiety Disorders

0.300

Biomarker

group

CTD_human

Progesterone modulation of alpha5 nAChR subunits influences anxiety-related behavior during estrus cycle.

19220484

2009