Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.030 AlteredExpression disease BEFREE Insulin directly upregulates URAT1 and downregulates ABCG2 in the kidney tubules, suggesting a possible link between UA and metabolic syndrome. 29393121 2018
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.030 GeneticVariation disease BEFREE The URAT1 gene SLC22A12 polymorphism may play a role in obesity and the metabolic syndrome in Caucasian hypertensive subjects. 22688828 2012
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.030 GeneticVariation disease BEFREE This study sought to determine the association between the novel G109T polymorphism in SLC22A12 with serum uric acid and the development of metabolic syndrome in Korean male subjects. 21544634 2012