Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 AlteredExpression disease BEFREE TWIST2 overexpression enhanced EMT and the invasive potential of the CRC LoVo and HCT116 cells, while TWIST2 knockdown reversed the EMT process and weakened the invasive potential of the cells. 30556860 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 PosttranslationalModification disease BEFREE TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer. 25528769 2015
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 AlteredExpression disease BEFREE Up-regulation of TWIST2 was detected in CRC tumors compared with adjacent normal tissues (P < 0.001) and is inversely correlated with miR-138 expression. 24171926 2013
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 Biomarker disease BEFREE Our data suggests, for the first time, that Twist2 is a valuable prognostic biomarker for CRC, particularly for patients in stage III and IV. 23613636 2013