CLCA1, chloride channel accessory 1, 1179

N. diseases: 42; N. variants: 1
Disease: airway disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699949
Disease: airway disease
airway disease 		0.030 Biomarker disease BEFREE CLCA1 has been shown to participate in the pathogenesis of inflammatory airway diseases such as asthma. 30952704 2019
CUI: C0699949
Disease: airway disease
airway disease 		0.030 AlteredExpression disease BEFREE In addition to its ability to upregulate cytokine expression which explains previous observations in the Clca1-deficient S. aureus pneumonia mouse model, modulation of BPIFA1 expression expands the role of CLCA1 in airway disease to involvement in more complex downstream pathways, possibly including liquid homeostasis, airway protection, and antimicrobial defense. 29610986 2018
CUI: C0699949
Disease: airway disease
airway disease 		0.030 Biomarker disease BEFREE CLCA1 and TMEM16A: the link towards a potential cure for airway diseases. 26296094 2015