CLU, clusterin, 1191

N. diseases: 412; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.030 Biomarker disease BEFREE Thus, clusterin plays an important role in hepatic fibrosis. 31739636 2019
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.030 AlteredExpression disease BEFREE We find increased core fucosylation of 5 glycopeptides at the stage of liver fibrosis (i.e., N630 of serotransferrin, N107 of alpha-1-antitrypsin, N253 of plasma protease C1 inhibitor, N397 of ceruloplasmin, and N86 of vitronectin), increase of additional 6 glycopeptides at the stage of cirrhosis (i.e., N138 and N762 of ceruloplasmin, N354 of clusterin, N187 of hemopexin, N71 of immunoglobulin J chain, and N127 of lumican), while the degree of core fucosylation of 10 glycopeptides did not change. 29427759 2018
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.030 AlteredExpression disease BEFREE Clusterin expression in cholestasis, hepatocellular carcinoma and liver fibrosis. 19413638 2009