TPH2, tryptophan hydroxylase 2, 121278

N. diseases: 137; N. variants: 37
Disease: Sudden infant death syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038644
Disease: Sudden infant death syndrome
Sudden infant death syndrome 		0.020 AlteredExpression disease BEFREE Brainstem serotonin (5-HT) and tryptophan hydroxylase-2 (TPH-2) levels have been shown to be lower in SIDS, supporting the evidence that defects in the medullary serotonergic system play a significant role in SIDS. 28111624 2016
CUI: C0038644
Disease: Sudden infant death syndrome
Sudden infant death syndrome 		0.020 Biomarker disease LHGDN Genes regulating the serotonin metabolic pathway in the brain stem and their role in the etiopathogenesis of the sudden infant death syndrome. 18387780 2008