Peripheral ossifying fibroma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The role of Osterix protein in the pathogenesis of peripheral ossifying fibroma.
|
28678972 |
2017 |
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Characterizing rare and low-frequency height-associated variants in the Japanese population.
|
31562340 |
2019 |
Bone Density
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.
|
19801982 |
2009 |
Bone Density
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.
|
19801982 |
2009 |
Bone Density
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
New sequence variants associated with bone mineral density.
|
19079262 |
2009 |
Bone Density
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
|
22504420 |
2012 |
Bone Density
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
New sequence variants associated with bone mineral density.
|
19079262 |
2009 |
Bone Mineral Density Test
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Meta-analysis of gene-based genome-wide association studies of bone mineral density in Chinese and European subjects.
|
21927923 |
2012 |
Bone Mineral Density Test
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
|
22504420 |
2012 |
Late tooth eruption
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Short stature
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Facial asymmetry
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Depressed nasal bridge
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Prominent forehead
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Prominent supraorbital ridges
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Progressive hearing impairment
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Midface retrusion
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Motor delay
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Brachyturricephaly
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Short Stature, CTCAE
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
We used quantitative real-time polymerase chain reaction to evaluate the gene expression of MDM2, CXCR4, RANKL, RB1, and OSTERIX in 98 samples of osteosarcoma taken from 47 patients (74 metastases and 24 primary tumors) and 30 nonmalignant lung tissues surrounding osteosarcoma metastases.
|
23845465 |
2013 |
Nodule
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Interestingly, rapamycin in rapamycin plus lipopolysaccharide (LPS)‑treated BMSCs significantly increased the gene expression levels of Sp7 transcription factor, runt related transcription factor 2, alkaline phosphatase (ALP) and collagen I (Col I), ALP activity, and calcium nodule at different time points in vitro, indicating that osteoblast differentiation occurs by rapamycin when BMSCs are exposed to LPS simultaneously.
|
28990080 |
2017 |
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Transfection of the osx gene into the mouse osteosarcoma cells inhibited tumor cell growth in vitro and in vivo and significantly reduced tumor incidence, tumor volume, and lung metastasis following intratibial injection.
|
15734992 |
2005 |
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Tumor-induced bone was reduced in trigenic mice (Tie2<sup>cre</sup>/Osx<sup>f/f</sup>/SCID) with endothelial-specific deletion of osteoblast cell-fate determinant OSX compared with bigenic mice (Osx<sup>f/f</sup>/SCID).
|
28586644 |
2017 |
Bone Diseases
|
0.010 |
AlteredExpression
|
group |
LHGDN |
Negative regulation of the osteoblast function in multiple myeloma through the repressor gene E4BP4 activated by malignant plasma cells.
|
18829486 |
2008 |