CMA1, chymase 1, 1215

N. diseases: 157; N. variants: 2
Disease: Eczema ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013595
Disease: Eczema
Eczema 		0.050 GeneticVariation disease BEFREE Previous studies have indicated that CMA1 promoter polymorphism rs1800875 may be involved in regulating immunoglobulin E (IgE) levels in patients with eczema, and it is associated with the progression of immunoglobulin A nephropathy. 21796807 2011
CUI: C0013595
Disease: Eczema
Eczema 		0.050 GeneticVariation disease BEFREE These data suggest that CMA1 promoter polymorphism does not contribute to asthma susceptibility or severity but may be involved in regulating IgE levels in patients with eczema. 15248847 2004
CUI: C0013595
Disease: Eczema
Eczema 		0.050 GeneticVariation disease BEFREE Absence of association between a variant of the mast cell chymase gene and atopic dermatitis in an Italian population. 11173969 2001
CUI: C0013595
Disease: Eczema
Eczema 		0.050 AlteredExpression disease BEFREE Association between variants of mast cell chymase gene and serum IgE levels in eczema. 9463800 1998
CUI: C0013595
Disease: Eczema
Eczema 		0.050 GeneticVariation disease BEFREE No evidence for an association between a variant of the mast cell chymase gene and atopic dermatitis based on case-control and haplotype-relative-risk analyses. 9748697 1998