PLD4, phospholipase D family member 4, 122618

N. diseases: 12; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis
0.010 Biomarker disease BEFREE Furthermore, therapeutic targeting of PLD4 using specific siRNA protected mice from folic acid-induced kidney fibrosis and inhibited the increase in TGF-<i>β</i> signaling, decrease in NE expression, and upregulation of mitogen-activated protein kinase signaling. 28814511 2017