Disease: Cholestasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.330 Biomarker disease BEFREE Organic solute transporter-β (SLC51B) deficiency in two brothers with congenital diarrhea and features of cholestasis. 28898457 2018
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.330 Biomarker disease BEFREE In this article, we review the potential clinical implications of the major BS transporters BSEP, OSTα/OSTβ and NTCP in the pathogenesis of hereditary and acquired cholestatic syndromes, provide an overview on transcriptional control of these transporters by the key regulatory nuclear receptors and discuss the potential therapeutic role of novel transcriptional activators of BS transporters in cholestasis. 24333169 2014
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.330 Biomarker disease CTD_human Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury. 22461449 2012
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.330 Biomarker disease CTD_human Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents. 16423920 2006
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.330 AlteredExpression disease LHGDN Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents. 16423920 2006