CCR8, C-C motif chemokine receptor 8, 1237

N. diseases: 67; N. variants: 1
Disease: Systemic Scleroderma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.020 AlteredExpression disease BEFREE Many T and B cells and some plasmacytes expressed CCR8 in LSGs of IgG4-RD and pSS patients. 31203743 2019
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.020 Biomarker disease BEFREE Three orthologues of genes implicated in human SSc are located in the QTL region on chromosome 2, TGFRB1, EXOC2-IRF4 and COL1A2, as well as CCR8, which is more generally related to immune function. 22796227 2012