Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement
0.100 GeneticVariation phenotype GWASCAT Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936. 31320639 2019
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections
0.010 Biomarker group BEFREE Receptor CD300b is implicated in regulating the immune response to bacterial infection by an unknown mechanism. 27261276 2016
CUI: C0036690
Disease: Septicemia
Septicemia
0.010 Biomarker disease BEFREE In vivo depletion and adoptive transfer studies identified CD300b-expressing macrophages as the key cell type augmenting sepsis. 27261276 2016
CUI: C0243026
Disease: Sepsis
Sepsis
0.010 Biomarker disease BEFREE In vivo depletion and adoptive transfer studies identified CD300b-expressing macrophages as the key cell type augmenting sepsis. 27261276 2016
CUI: C0919747
Disease: Cytokine storm
Cytokine storm
0.010 Biomarker disease BEFREE We showed that CD300b, and its adaptor DAP12, associated with Toll-like receptor 4 (TLR4) upon LPS binding, thereby enhancing TLR4-adaptor MyD88- and TRIF-dependent signaling that resulted in an elevated pro-inflammatory cytokine storm. 27261276 2016