CNR1, cannabinoid receptor 1, 1268

N. diseases: 393; N. variants: 21
Disease: Diabetic Nephropathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.040 Biomarker disease BEFREE These findings have the potential to be translated into therapy, and support the rationale for the preclinical development of novel renal-specific CB1R and/or GLUT2 inhibitors for the treatment of DN. 30636250 2019
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.040 Biomarker disease BEFREE Preclinical studies confirm that both CB1R and CB2R are implicated in the pathogenesis of DKD and may represent novel targets for treatment. 29399721 2018
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.040 Biomarker disease BEFREE 'Peripheral' CB1R blockade is beneficial in experimental DN and this effect is synergically magnified by CB2R activation. 28387811 2017
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.040 Biomarker disease BEFREE Our results provide evidence that CB(1)R blockade may be a potential anti-diabetic therapy for the treatment of DN. 20506110 2010