CNR1, cannabinoid receptor 1, 1268

N. diseases: 393; N. variants: 21
Disease: Fatty Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 Biomarker disease BEFREE Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2. 31570772 2020
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 Biomarker disease BEFREE Additionally, blocking peripheral CB1R improves insulin sensitivity and glucose metabolism and also reduces hepatic steatosis and body weight in obese mice. 31035653 2019
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 Biomarker disease BEFREE However, the beneficial effects of CB1 receptor blockade on hepatic steatosis and inflammation have not been investigated independently of its effects on body weight and glycemic control. 30365523 2018
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 Biomarker disease BEFREE The aim of this study was to explore the potential pathways altered with CB1R in obesity-induced fatty liver. 27928909 2017
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 Biomarker disease BEFREE This study is the first to report CB1R as a potential hepatic stimulator for zebrafish liver steatosis. 23315130 2013