CNTF, ciliary neurotrophic factor, 1270

N. diseases: 114; N. variants: 3
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.040 Biomarker disease BEFREE One cytokine in particular, ciliary neurotrophic factor (CNTF), acts both centrally and peripherally and mimics the biologic actions of the appetite control hormone leptin, but unlike leptin, CNTF appears to be effective in obesity and as such may have therapeutic potential. 17404609 2007
CUI: C0028754
Disease: Obesity
Obesity 		0.040 Biomarker disease BEFREE Genetic variation in the peroxisome proliferator-activated receptor gamma2 (PPARgamma2), glucocorticoid receptor (GRL), and ciliary neurotrophic factor (CNTF) genes may play a role in the etiology of obesity. 16210701 2005
CUI: C0028754
Disease: Obesity
Obesity 		0.040 GeneticVariation disease BEFREE In conclusion, variants in the CNTF gene are unlikely to be associated with the development of early-onset obesity. 9628240 1998
CUI: C0028754
Disease: Obesity
Obesity 		0.040 Biomarker disease BEFREE Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance. 9177239 1997