COL1A1, collagen type I alpha 1 chain, 1277

N. diseases: 487; N. variants: 337
Disease: Liver Cirrhosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.320 GeneticVariation disease BEFREE Our results suggest a model in which cirrhosis results in a general loss of permissive chromatin histone marks which triggers the repression of the Pparg gene and the upregulation of the Col1a1 gene. 28590037 2018
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.320 Biomarker disease CTD_human Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. 26396155 2016
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.320 Biomarker disease CTD_human Ascorbic acid suppresses endotoxemia and NF-κB signaling cascade in alcoholic liver fibrosis in guinea pigs: a mechanistic approach. 24239723 2014
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.320 Biomarker disease CTD_human Precision-cut liver slices as a model for the early onset of liver fibrosis to test antifibrotic drugs. 24321339 2014
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.320 Biomarker disease CTD_human Cannabinoid receptor type I modulates alcohol-induced liver fibrosis. 21863215 2011
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.320 GeneticVariation disease BEFREE Study of the association between polymorphisms of the COL1A1 gene and HBV-related liver cirrhosis in Chinese patients. 18536987 2009