COL4A2, collagen type IV alpha 2 chain, 1284

N. diseases: 131; N. variants: 38
Disease: Stroke, Lacunar ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3178801
Disease: Stroke, Lacunar
Stroke, Lacunar 		0.020 Biomarker disease BEFREE This study demonstrates that the COL4A2 gene could play a role in the pathogenesis of lacunar stroke in the Han population of China. 31214923 2019
CUI: C3178801
Disease: Stroke, Lacunar
Stroke, Lacunar 		0.020 GeneticVariation disease BEFREE T2D was associated with higher risk of lacunar stroke (odds ratio [OR], 1.15; 95% confidence interval [CI], 1.04-1.28; <i>P</i>=0.007) and lower mean FA (OR, 0.78; 95% CI, 0.66-0.92; <i>P</i>=0.004) but not white matter hyperintensities volume (OR, 1.01; 95% CI, 0.97-1.04; <i>P</i>=0.626), higher mean diffusivity (OR, 1.04; 95% CI, 0.89-1.23; <i>P</i>=0.612), ICH (OR, 1.07; 95% CI, 0.95-1.20; <i>P</i>=0.269), lobar ICH (OR, 1.07; 95% CI, 0.89-1.28; <i>P</i>=0.466), or deep ICH (OR, 1.16; 95% CI, 0.99-1.36; <i>P</i>=0.074). 29686024 2018