ADORA2A, adenosine A2a receptor, 135

N. diseases: 213; N. variants: 10
Disease: Diabetes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes 		0.020 Biomarker disease BEFREE These findings indicate that Adora2a-mediated signaling in endothelial cells mediates obesity-induced BBB breakdown, and implicate cerebrovascular dysfunction as the mechanism for deficits in synaptic plasticity and cognition with obesity and diabetes. 30886019 2019
CUI: C0011847
Disease: Diabetes
Diabetes 		0.020 AlteredExpression disease BEFREE Our data suggest that diabetes resulted in an increased A2AAR expression in coronary arteries which resulted in enhanced A2AAR-mediated increase in CF observed in diabetic hearts. 26654777 2016