CPB2, carboxypeptidase B2, 1361

N. diseases: 148; N. variants: 11
Disease: Hypercholesterolemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.020 AlteredExpression disease BEFREE In Ppara-null mice, the HC diet caused triglyceride accumulation and exacerbated inflammation and oxidative stress in liver, increased levels of coagulation factors, including tissue factor, plasminogen activator inhibitor-1 and carboxypeptidase B2 in blood and liver, and decreased levels of anti-thrombotic sulfatides in serum and liver. 30341732 2019
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.020 Biomarker disease LHGDN Coexistence of MS and HC synergistically accelerates inflammation and impairment of fibrinolysis via elevated concentrations of both TAFI and PAI-1, which inhibit fibrinolysis. 16123492 2005