CPB2, carboxypeptidase B2, 1361

N. diseases: 148; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162871
Disease: Aortic Aneurysm, Abdominal
Aortic Aneurysm, Abdominal
0.030 Biomarker disease BEFREE Inhibition of plasmin-mediated TAFI activation reduced the incidence of AAA from 52.4% to 30.0%. 28472123 2017
CUI: C0162871
Disease: Aortic Aneurysm, Abdominal
Aortic Aneurysm, Abdominal
0.030 Biomarker disease BEFREE Methods Plasma levels of TAFI, TAFI activation peptide (TAFI-AP), activated/inactivated TAFI (TAFIa/ai) and plasmin-α2-antiplasmin complex were measured by ELISAs in patients with AAA (n = 202) and controls (n = 188). 28834317 2017
CUI: C0162871
Disease: Aortic Aneurysm, Abdominal
Aortic Aneurysm, Abdominal
0.030 GeneticVariation disease BEFREE The TAFI Thr325Ile and the tPA 7351C→T polymorphisms were not associated with AAA. 25065555 2014