CPB2, carboxypeptidase B2, 1361

N. diseases: 148; N. variants: 11
Disease: Antibiotic-associated diarrhea ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0578159
Disease: Antibiotic-associated diarrhea
Antibiotic-associated diarrhea 		0.030 Biomarker disease BEFREE Notably, 41.2% of type F strains were also cpb2-positive and enterotoxigenic cpe-positive strains were detected in 13.2% of the isolates from AAD patients. 31127185 2019
CUI: C0578159
Disease: Antibiotic-associated diarrhea
Antibiotic-associated diarrhea 		0.030 Biomarker disease BEFREE A recent study reported the association of beta2 toxin (CPB2) with human GI diseases, and particularly AAD/SD, by demonstrating that a large percentage of AAD/SD isolates, in contrast to a small percentage of food poisoning isolates, carry the beta2-toxin gene (cpb2). 16332823 2005
CUI: C0578159
Disease: Antibiotic-associated diarrhea
Antibiotic-associated diarrhea 		0.030 Biomarker disease BEFREE Collectively, these results suggest that CPB2 could be an accessory toxin in C. perfringens enterotoxin (CPE)-associated AAD/SD. 15819629 2005