ATF2, activating transcription factor 2, 1386

N. diseases: 122; N. variants: 17
Disease: CNS disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007682
Disease: CNS disorder
CNS disorder 		0.010 Biomarker group BEFREE Taken together, our data first proved the pro-inflammatory function of ATF2 in microglia, and suggested that the TRAF6-JNK/p38-ATF2 axis might promote microglial inflammatory activation and thus aggravate neuronal injury in brain, which might become a potential therapeutic target for CNS diseases. 30763583 2019