ATF2, activating transcription factor 2, 1386

N. diseases: 122; N. variants: 17
Disease: Skin Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0037286
Disease: Skin Neoplasms
Skin Neoplasms 		0.020 Biomarker group BEFREE Activating transcription factor 2 (ATF2; also known as cAMP-dependent transcription factor ATF-2) has oncogenic activities in melanoma and tumor suppressor activities in non-malignant skin tumors and breast cancer. 22685333 2012
CUI: C0037286
Disease: Skin Neoplasms
Skin Neoplasms 		0.020 Biomarker group BEFREE Yet work in other tumor models, including breast and skin tumors reveals that ATF2, in cooperation with mutated oncogenes or tumor suppressor genes, can also elicit tumor suppressor function. 18677098 2008