CRMP1, collapsin response mediator protein 1, 1400

N. diseases: 148; N. variants: 42
Disease: Malignant Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker group BEFREE Then, siRNA against Drp1 was transfected into cells to evaluate the influence of mitochondrial fission in cancer survival. 31127452 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 AlteredExpression group BEFREE DRP1 activity has recently been implicated as being dysregulated in numerous human disorders such as cancer and neurodegenerative diseases. 29290987 2017
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker group BEFREE Our Drp1-directed large-scale analyses of the publically available cancer genomes reveal a robust correlation of Drp1 with cell-cycle genes in 29 of the 31 cancer types examined. 27509055 2016
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 AlteredExpression group BEFREE Recently, members of the DPYSL family have been reported to be involved in cancer with low expression of DPYSL1 correlating with poor clinical outcomes in non-small cell lung cancer and functioning as a metastasis suppressor. 24011394 2013
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker group BEFREE A receptor tyrosine kinase inhibitor, Tyrphostin A9 induces cancer cell death through Drp1 dependent mitochondria fragmentation. 21527248 2011
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker group BEFREE Collapsin response mediator protein-1 (CRMP-1) controls neural development and axonal growth but also acts as a cancer invasion suppressor. 18524846 2008
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker group BEFREE Previously, we used microarray to identify that collapsin response mediator protein-1 (CRMP-1) was involved in cancer invasion and metastasis. 12650609 2003
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker group BEFREE CRMP-1 appears to be involved in cancer invasion and metastasis and may be an invasion-suppressor gene. 11562390 2001