ISM1, isthmin 1, 140862

N. diseases: 14; N. variants: 2
Disease: Leukemia, Mast-Cell ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023461
Disease: Leukemia, Mast-Cell
Leukemia, Mast-Cell 		0.020 Biomarker disease BEFREE Broadly, patients either have indolent/smoldering SM (ISM/SSM) or advanced SM, the latter includes aggressive SM (ASM), SM with associated hematological neoplasm (SM-AHN), and mast cell leukemia (MCL). 30536695 2019
CUI: C0023461
Disease: Leukemia, Mast-Cell
Leukemia, Mast-Cell 		0.020 Biomarker disease BEFREE This leads to a wide variety of clinical manifestations resulting from excessive mediator release in CM and benign forms of SM (indolent SM, ISM) and from tissue mast cell infiltration causing multiorgan dysfunction and failure in more aggressive subtypes (aggressive SM, ASM, or mast cell leukemia). 28775983 2017